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Third Plague Pandemic begins in Yunnan

1855 (origin in Yunnan); global spread from 1894·Science, technology & invention·Yunnan, China (global spread)·
1855 (origin in Yunnan); global spread from 1894Date
Science, technology & inventionCategory
27Empires active
Date
1855 (origin in Yunnan); global spread from 1894
Category
Science, technology & invention
Region
Yunnan, China (global spread)
Era
Modern
Significance

The Third Plague Pandemic, the last of the three great bubonic plague pandemics caused by the bacterium Yersinia pestis, originated in China's Yunnan province around 1855, where mining booms and rising trade brought people into contact with plague-infected rats and fleas.

The disease spread along regional trade routes and reached Hong Kong and Guangzhou in 1894, from where ocean-going steamships carried infected rats and fleas to ports across every inhabited continent, including Bombay, San Francisco, and Sydney. The Hong Kong epidemic of 1894 prompted a scientific breakthrough when Alexandre Yersin and Kitasato Shibasaburo independently isolated the causative bacterium, later named Yersinia pestis, and in 1898 Paul-Louis Simond demonstrated that fleas transmitted the disease from rats to humans. The pandemic ultimately killed at least 15 million people, with roughly 10-12 million deaths in British India and about 2.2 million in China. The World Health Organization considered the pandemic active until 1960, when annual worldwide deaths fell below 200, though Yersinia pestis became permanently established in wild rodent populations on several continents.

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Empires active in 1855 (origin in Yunnan); global spread from 1894

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