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The Discovery Of Oral Rehydration Therapy

1968·Science, technology & invention·South Asia (Bangladesh)·
1968Date
Science, technology & inventionCategory
7Empires active
Date
1968
Category
Science, technology & invention
Region
South Asia (Bangladesh)
Era
Contemporary
Significance

In 1968 clinical trials in Dhaka, published in The Lancet, demonstrated that a simple solution of water, salt, and sugar could treat the lethal dehydration of cholera and diarrhoea, a breakthrough the journal later hailed as potentially the most important medical advance of the twentieth century.

Researchers David Nalin and Richard Cash, working at the cholera research laboratory in East Pakistan (now Bangladesh) alongside colleagues in Calcutta, showed that glucose enables the gut to absorb water and salts even during acute infection, so patients could be rehydrated orally rather than through scarce and costly intravenous drips. The method's genius lay in its cheapness and simplicity: it required no hospital, no sterile equipment, and could be administered by families anywhere. Deployed during a cholera epidemic among Bangladeshi refugees in 1971 with dramatic results, oral rehydration therapy spread worldwide through UNICEF and the World Health Organization. It has since been credited with preventing tens of millions of deaths, overwhelmingly of young children, and remains one of the most cost-effective life-saving interventions ever devised.

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